Celeste
Unregistered User
(11/24/02 11:04 pm)
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Fibromuscular Dysplasia link
www.med.uc.edu/neurorad/webpage/goa.html
Fibromuscular Dysplasia
Findings:
Bilateral common carotid arteriograms show irregular beaded stenoses of the internal carotid arteries. The external carotid arteries show minimal irregularity as well.
Differential Diagnosis:
The appearance is fairly characteristic for fibromuscular dysplasia. Atherosclerotic disease would be more common overall, but the location of disease would be atypical.
Discussion:
Fibromuscular dysplasia most commonly involves the renal arteries of middle aged females, and represents an idiopathic proliferation of the intima and/or media. Subtypes of this disease include intimal hyperplasia, medial fibroplasia, fibromuscular hyperplasia, and subadventitial fibroplasia, of which medial fibroplasia is the most common. The medial fibroplasia type causes the typical "string of beads" appearance. 3% of cases involve the internal carotids between the middle and distal thirds, with a 25% incidence of intracranial aneurysms in these patients. Embolic strokes may be seen as well. The vertebral arteries may also be involved, but this is less common. Bilateral involvement is common.
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